Syria’s national security chief has died of wounds suffered in a rebel blast, the Associated Press reported citing the local TV.

Gen. Hisham Ikhtiyar is the fourth member of President Bashar Assad's inner circle to die in Wednesday's bombing that targeted security chiefs meeting in the national security headquarters in Damascus.

The TV report says Ikhtiyar died Friday, July 20 morning.

The others killed in the blast were Gen. Assef Shawkat, the deputy defense minister who was married to Assad's elder sister, Defense Minister Dawoud Rajha and Hassan Turkmani, a former defense minister.