Iran's Supreme Leader has said Tehran will not negotiate with the United States on any issue after the landmark nuclear deal with world powers in July, according to his official website on Wednesday, September 9, Reuters reports.

The comments appeared to contradict more moderate president Hassan Rouhani, who said on Tuesday the Islamic Republic was ready to hold talks with the United States on ways to resolve Syria's civil war.

"We negotiated with the U.S. on the nuclear issue for specific reasons. (The Americans) behaved well in the talks, but we didn't and we won't allow negotiation with the Americans on other issues," Ayatollah Khamenei was quoted as saying.

"The Americans are not hiding their animosity towards Iran... Negotiations are a tool for them to influence Iran and to impose their will," Ayatollah Khamenei said to hundreds of visitors to his offices.