At least 20 civilians were killed late Wednesday, April 27 in regime strikes on a hospital and nearby residential building in the Syrian city of Aleppo, civil defense volunteers known as the White Helmets said, according to AFP.

A dentist and five members of a family, including two children, were among those killed "by airstrikes targeting al Quds Hospital and a nearby residential building in al Sukkari neighbourhood in eastern Aleppo," the volunteers told AFP.

A doctor who was the only paediatrician in the rebel-held eastern neighborhoods of Aleppo was also among the dead, an AFP correspondent on the ground said.

The Syrian Observatory for Human Rights monitoring group confirmed the raids were carried out by "regime airplanes" and said two hospital guards and a doctor were among the dead.

Video footage filmed by AFP showed images of the badly damaged hospital, aid workers transporting the victims in ambulances and a weeping man holding a child, Reuters says.

Rescuers were at the scene searching for victims trapped under the rubble, the AFP correspondent said.

Separately, 11 people were killed in western parts of Aleppo earlier on Wednesday, according to the Syrian Observatory. State news agency SANA blamed the rocket and gunfire on Al-Qaeda affiliate Al-Nusra Front and its allies.

Also earlier in the day, five civilians were killed in two neighborhoods in eastern Aleppo, according to the White Helmets. An AFP correspondent said that regime aircraft targeted one area with barrel bombs and another with missiles.

Following a lull in fighting after the ceasefire took effect on February 27, violence has intensified in recent days, with more than 100 civilians reported dead in air strikes, shelling and rocket fire since Friday.