British scientists develop virus that "kills cancer cells"November 19, 2018 - 12:59 AMT PanARMENIAN.Net - A genetically modified virus that kills cancer cells and destroys their hiding places has been developed by British scientists, The Sun says. It targets both cancer cells and healthy cells that are tricked into protecting the cancer from the immune system. The role of fibroblasts is to hold different types of organs together but they can get hijacked by cancer cells to become cancer-associated fibroblasts or CAFs. These are then known to help tumours grow, spread and evade therapy. The virus, developed by Oxford University scientists, attacks carcinomas, which are the most common type of cancer. Currently, any therapy that kills the 'tricked' fibroblast cells may also kill fibroblasts throughout the body - for example in the bone marrow and skin - causing toxicity. So researchers used a virus called enadenotucirev, which is already in clinical trials for treating carcinomas. It has been bred to infect only cancer cells, leaving healthy cells alone. Lecturer Dr Kerry Fisher also from the Department of Oncology who led the research said: "Even when most of the cancer cells in a carcinoma are killed, fibroblasts can protect the residual cancer cells and help them to recover and flourish. "Until now, there has not been any way to kill both cancer cells and the fibroblasts protecting them at the same time, without harming the rest of the body. Top stories Authorities said a total of 192 Azerbaijani troops were killed and 511 were wounded during Azerbaijan’s offensive. In 2023, the Azerbaijani government will increase the country’s defense budget by more than 1.1 billion manats ($650 million). The bill, published on Monday, is designed to "eliminate the shortcomings of an unreasonably broad interpretation of the key concept of "compatriot". The earthquake caused a temporary blackout, damaged many buildings and closed a number of rural roads. Partner news | Czech-Armenian military cooperation discussed in Yerevan A delegation led by the Director General for the Industrial Cooperation Division of the Ministry of Defence of the Czech Republic visited Armenia. U.S. welcomes efforts to define Armenia-Azerbaijan border The United States welcomes efforts to define the border between Armenia and Azerbaijan, says Vedant Patel. Biden honors resilience of Armenian people on April 24 U.S. President Joe Biden has issued a statement on the 109th anniversary of the Armenian Genocide. Ex-Karabakh leader moved to solitary confinement cell in Baku, his son says David Vardanyan is the son of former Karabakh leader Ruben Vardanyan who who is currently imprisoned in Azerbaijan. |