Signs of cancer can appear long before diagnosis, study showsFebruary 6, 2020 - 12:35 AMT PanARMENIAN.Net - Early signs of cancer can appear years or even decades before diagnosis, according to the most comprehensive investigation to date of the genetic mutations that cause healthy cells to turn malignant, The Guardian reports. The findings, based on samples from more than 2,500 tumors and 38 cancer types, reveal a longer-than-expected window of opportunity in which patients could potentially be tested and treated at the earliest stages of the disease. The work was carried out as part of the Pan-Cancer Analysis of Whole Genomes project, the most comprehensive study of cancer genetics to date. “What’s extraordinary is how some of the genetic changes appear to have occurred many years before diagnosis, long before any other signs that a cancer may develop, and perhaps even in apparently normal tissue,” said Clemency Jolly, a co-author of the research based at the Francis Crick Institute in London. “Unlocking these patterns means it should now be possible to develop new diagnostic tests that pick up signs of cancer much earlier,” said Peter Van Loo, co-lead author, also of the Crick Institute. “There is a window of opportunity.” The discovery that the seeds of cancer are often sown many years before the first symptoms arise will not change cancer screening in the immediate term. But it points to the possibility that those at risk could be spotted far earlier. Top stories Authorities said a total of 192 Azerbaijani troops were killed and 511 were wounded during Azerbaijan’s offensive. In 2023, the Azerbaijani government will increase the country’s defense budget by more than 1.1 billion manats ($650 million). The bill, published on Monday, is designed to "eliminate the shortcomings of an unreasonably broad interpretation of the key concept of "compatriot". The earthquake caused a temporary blackout, damaged many buildings and closed a number of rural roads. Partner news | Government reveals details from Pashinyan’s meeting in border village Prime Minister Nikol Pashinyan has met with a group of residents of a border village in Armenia’s northern Tavush province Narek Manasyan wins European Boxing Championships silver for Armenia Armenia’s Narek Manasyan (92kg) won Armenia’s second silver medal at the European Boxing Championships 2024 on April 28. Blinken urges Azerbaijan to continue negotiations with Armenia Secretary of State Antony J. Blinken has urged Azerbaijani President Ilham Aliyev to continue negotiations with Armenia. Pashinyan, Blinken talk Armenia-U.S. ties over the phone Prime Minister Nikol Pashinyan had a phone conversation with US Secretary of State Antony Blinken on April 28, Pashinyan’s office reports. |